Letrozole, sold under the brand name Femara, is a prescription drug used to treat breast cancer in its advanced stages, and in women who have finished menopause.
Doctors may use letrozole off-label in fertility treatments to help encourage egg release (ovulation) in women.
Letrozole belongs to a class of cancer drugs known as aromatase inhibitors, which work by preventing the body from converting a hormone called androgen into estrogen.
This treatment has proven beneficial in cancers whose growth seems to be encouraged by excess estrogen in the body, like certain types of breast cancer.
Letrozole comes in tablets of 2.5 milligrams (mg).
How much letrozole your doctor tells you to take may vary, but for cancer, a usual dose is 2.5 mg a day.
If you’re taking letrozole for fertility treatment, your doctor may tell you to take either 2.5 mg or 5 mg of the drug, beginning on the third day of your period for five days.
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